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Fmoc-NH-PEG8-CH2CH2COOH
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Fmoc-NH-PEG8-CH2CH2COOH图片
CAS NO:756526-02-0
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
Fmoc-NH-PEG8-CH2CH2COOH 是一种可降解的 ADC linker，用于抗体药物偶联物 (ADC) 合成。
Cas No.756526-02-0
分子式C34H49NO12
分子量663.75
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.