重组TP53调节激酶蛋白

立即咨询

重组TP53调节激酶蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant TP53RK
Recombinant TP53 regulating kinase protein

产品介绍

基因名：

TP53RK

产品别名：

BUD32； C20orf64； GAMOS4； Nori-2； Nori-2p； PRPK； TPRKB； dJ101A2； TP53RK； TP53 regulating kinase； TP53 regulating kinase； EKC/KEOPS complex subunit TP53RK； atypical serine/threonine protein kinase TP53RK； p53-related protein kinase； TP53调节激酶；

背景信息：

PRPK is a 253 amino acid protein kinase that phosphorylates Ser15 of p53. PRPK phosphorylation of p53 causes increased stabilization and activity of p53. CGI-121 may act as an inhibitor of the PRPK-p53 interaction, thus preventing the phosphorylation of p53. Unphosphorylated p53 is degraded by the ubiquitin-proteasome pathway, which may ultimately lead to cell proliferation. PRPK contains a protein kinase domain with a conserved catalytic core. PRPK is localized to the nucleus of the cell and is highly expressed in testis, with lower expression in heart, kidney and spleen.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。