LARGE1抗体

立即咨询

LARGE1抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Anti-LARGE1
Anti-LARGE xylosyl- and glucuronyltransferase 1 Antibody

产品介绍

靶标：

LARGE1

产品别名：

LARGE； MDC1D； MDDGA6； MDDGB6； LARGE1； LARGE xylosyl- and glucuronyltransferase 1； LARGE xylosyl- and glucuronyltransferase 1； xylosyl- and glucuronyltransferase LARGE1； acetylglucosaminyltransferase-like 1A； acetylglucosaminyltransferase-like protein； glycosyltransferase-like protein LARGE1；

背景信息：

LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。