Ac2-26 TFA，是膜联蛋白 A1 (AnxA1) 的活性 N-末端肽，可减轻缺血再灌注诱导的急性肺损伤。Ac2-26 还降低 AnxA1 蛋白表达，抑制受损肺组织中 NF-κB 和 MAPK 通路活化。
货号:ajcx13688
CAS:N/A
分子式:C143H211F3N32O46S
分子量：3203.45
溶解度:H2O : 0.11 mg/mL; DMSO :< 1 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Ac2-26 TFA, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. Ac2-26 also decreases AnxA1 protein expression, inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue[1].

[1]. Liao WI, et al. Ac2-26, an Annexin A1 Peptide, Attenuates Ischemia-Reperfusion-Induced Acute Lung Injury. Int J Mol Sci. 2017 Aug 15;18(8). pii: E1771.