PROTAC FKBP Degrader-3 是一种包含 FKBP 配体结合基团，linker 和 VHL 结合基团的 PROTAC。PROTAC FKBP Degrader-3 是一种有效的 FKBP 降解剂。
货号:ajcx16748
CAS:2079056-43-0
分子式:C68H90N6O17S
分子量：1295.54
溶解度:DMSO: 25 mg/mL (19.30 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].

[1]. Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.