Itacnosertib (TP-0184) 是JAK2，ACVR1 (ALK2)和ALK5的抑制剂，如WO2014151871所述。
货号:ajcx35636
CAS:1628870-27-8
分子式:C26H28N8O
分子量：468.55
溶解度:DMSO : 12.5 mg/mL (26.68 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Itacnosertib (TP-0184) is both inhibitor to JAK2, ACVR1 (ALK2) and ALK5 as described in WO2014151871[1].

[1]. Mollard, Alexis; Warner, Steven L.; Flynn, Gary A.; Vankayalapati, Hariprasad; Bearss, David J. Preparation of [(piperazinylphenyl)amino]pyrimidine derivatives as JAK2 and ALK2 inhibitors. WO2014151871 A2