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Azide-PEG3-Tos
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Azide-PEG3-Tos图片
CAS NO:178685-33-1
包装与价格:
包装价格(元)
100 mg电议
500 mg电议

产品介绍

产品描述

Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

体外活性

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

Cas No.

178685-33-1

分子式

C13H19N3O5S

分子量

329.37

别名

Azide-PEG3-Tos

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years