Mal-amIDO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].

PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

756525-99-2

C22H31N3O11

513.5

N-[15-[(2,5-二氧代-1-吡咯烷基)氧基]-15-氧代-3,6,9,12-四氧杂十五烷-1-基]-2,5-二氢-2,5-二氧代-1H-吡咯-1-丙酰胺;Mal-amido-PEG4-NHS ester

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years