Forasartan is a non - peptide angiotensin II receptor antagonist with antihypertensive activity. Forasartan and angiotensin II compete to bind AT1 receptor subtypes in vascular smooth muscle, thereby blocking angiotensin II-mediated vasoconstriction, leading to vasodilation. In addition, antagonism against AT1 in the adrenal gland prevents angiotensin II-induced adrenal cortical synthesis and aldosterone secretion stimulation.

145216-43-9

C23H28N8

416.52

SC-52458;SC52458;SC 52458;Forasartan

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years