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Bromo-PEG4-azide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Bromo-PEG4-azide图片
CAS NO:1951439-37-4
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
Bromo-PEG5-azide 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
Cas No.1951439-37-4
别名叠氮-四聚乙二醇-溴
Canonical SMILESBrCCOCCOCCOCCOCCN=[N+]=[N-]
分子式C10H20BrN3O4
分子量326.19
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562