二氯{（S )-(-)-2,2'- 双[二（3,5 - 二甲苯基）膦]-1,1' - 联萘} [（2S)-(+)-1,1-二（4

二氯{（S )-(-)-2,2'- 双[二（3,5 - 二甲苯基）膦]-1,1' - 联萘} [（2S)-(+)-1,1-二（4 - 甲氧基苯基）-3 -

Dichloro{(S)-(-)-2,2'-bis[di(3,5-xylyl)phosphino]-1,1'-binaphthyl}[(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II) RuCl?[(S)-xylbinap][(S)-daipen]

货号:J3444-0213

品牌:Strem

CAS NO:220114-01-2

分子式:C??H??Cl?N?O?P?Ru

分子量:1221.28

包装	价格
250mg	1080元	留言咨询
1g	3206元	留言咨询
5g	7999元	留言咨询

仅供研发或工业应用，不可直接用于食品、药品、临床诊断或治疗。

产品介绍

Technical Notes:

1.Highly active catalyst for hydrogenation of simple ketones giving high enantioselectivity when sterically unsymmetrical ketones such as acetophenone, heteroaryl ketones, benzophenones, cyclopropyl ketones, and cyclohexyl ketones are substrates. Ee's are enhanced with XyIBINAP relative to BINAP. The otherwise poorly bonded ketone is held in the transition state by hydrogen bonding to the protic bidentate amine.

2. Carbonyl groups are selectively reduced even when olefins exist in the s ame molecule.

3. In the presence of strong base, and catalyst, simple ketones, having substituents at the a-position, may be induced to undergo dynamic kinectic resolution during their hydrogenatio n toproduce , two chiral carbon centers in high yield.

References:

1. Angew Chem. Int. Ed.. 2001, 40, 40. (review article)

2.Org. Lott 2000, 2, 1749.

3.Org. Lott. 2000, 2, 659.

4.J. Am. Chem. Soc.. 1998. 120, 13529.

5.J. Am. Chem. Soc 2000, 122, 6510.

应用分类