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CAS: 58-96-8
分子式: C9H12N2O6
分子量: 244.20
熔点: 165-170℃
中文名称: 
尿苷
尿核苷
尿嘧啶核苷(尿苷)
尿嘧啶核苷
英文名称: 
Uridine
Uracil riboside
1-beta-d-ribofuranosyl-uraci
1-beta-d-ribofuranosyluracil
beta-uridine
uridin
1-D-Ribofuranosyl uracil
β-Uridine
性质描述: 该品为白色结晶性粉末或类白色结晶性粉末。熔点161-166℃。
用途: 尿苷是一种药物,如抗巨型红血球贫血,治疗肝、脑血管、心血管等疾病,也是制造氟尿嘧啶(S-FC)、脱氧核苷、碘苷(IDUR)、溴苷(BUDR)、氟苷(FUDR)等药物的主要原料。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
U796876MACKLIN尿嘧啶核苷10mM in DMSO524元/1ml;   展开
储存:-20°C
U820334MACKLIN尿嘧啶核苷99%29元/5g;   68元/25g;   159元/100g;   703元/500g;   3328元/2.5kg;   展开
储存:2~8°C
状态:白色到灰白色粉末
折射率:9 ° (C=2, H2O)
U6222MACKLIN尿苷99%生物技术级35元/5g;   112元/25g;   360元/100g;   1410元/500g;   展开
储存:2~8°C
状态:白色到灰白色粉末
折射率:9 ° (C=2, H2O)
U0020TCIUridine>98.0%(T)(HPLC)285元/5G;   870元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C9H12N2O6 = 244.20
外观与形状(20℃)固体
Reaxys-RN754904
PubChem物质ID87577750
SDBS (AIST Spectral DB)1167
Merck Index (14)9877
MDL编号MFCD00006526

技术规格

AppearanceWhite powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point165.0 to 169.0 ℃
Specific rotation [a]20/D+8.0 to +10.0 deg(C=2, H2O)
Solubility in Wateralmost transparency

物性(参考值)

熔点165 ℃
比旋光度 [α]D9° (C=2,H2O)
水溶性可溶
溶解性(微溶于)乙醇
溶解性(不溶于)乙醚

相关法规

RTECS#YR1450000
399796J&KUridine99%, 一种核苷化合物, 由尿嘧啶与核糖环组成, 两者由β-N1-配糖键相连73元/5G;   197元/25G;   526元/100G;   展开

基本信息

分子式C9H12N2O6
分子量244.20
熔点163-167
MDL编码MFCD00006526
Beilstein754902
Merck14,9877
EINECS 编号200-407-5

产品描述

Uridine是一种核苷,包含尿嘧啶,通过β-N1-糖苷键与核糖环连接。

靶点(IC50 & Targe)

LSm6

安全信息

防范说明P262
WGK3
RTECSYR1450000
TSCA
985493J&KUridine有效含量≥90%, 可溯源至中检院标准品72元/25MG;   展开

基本信息

分子式C9H12N2O6
分子量244.2
MDL编码MFCD00006526
A15227Alfa AesarUridine99%609元/5g;   2162元/25g;   7251元/100g;   展开

应用
Uridine plays a vital role in the glycolysis pathway of galactose. It is used as a precursor in the production of CDP-choline. It is an important nutrient and widely used as a dietary supplement. It improves brain cholinergic functions and hepatic mitochondrial function in certain liver toxins. It plays a major role in pain physiology and brain energy utilization to maintain ATP production under restricted oxygen conditions.

备注
Store in a cool place. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00006526

EINECS
200-407-5

分子式
C9H12N2O6

分子量
244.20

熔点
166-169°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in water, dimethylsulfoxide, and methanol.

Beilstein
754904

Merck
14,9877

安全信息

RTECS
YR1450000

TSCA

6680MilliporeUridine-CAS 58-96-8-Calbiochem1577.95元/25 G;   4408.98元/100 G;   展开

产品说明

包装

25, 100 g in Glass bottle

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C).

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C9H12N2O6
分子量244.20
MDL编号MFCD00006526

产品性质

质量水平100
测定≥97% (HPLC)
≥99% (UV)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
杂质≤1% ash
颜色 white to off-white
溶解性water: soluble
痕量阳离子heavy metals: <10 ppm
运输ambient
储存温度15-25℃
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)
InChI keyDRTQHJPVMGBUCF-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
U3750Sigma-AldrichUridine≥99%722.13元/1 G;   1592.16元/25 G;   4801.23元/100 G;   展开

产品说明

一般描述

尿苷是尿嘧啶核苷,对RNA序列有特异性。尿苷存在于血液、精液和脑脊液中。尿苷在生物体内通过从头合成和回收途径合成。

应用

尿苷已用于:

  • 作为海马神经元培养基组分用于培养原代海马神经元细胞
  • 小鼠胚胎成纤维细胞和人乳腺癌细胞的尿苷拯救实验
  • Chase测序实验

包装

1, 25, 100 g in poly bottle

生化/生理作用

单磷酸尿苷是蛋白糖基化、多糖生物合成和脂质代谢的必需成分。建议口服尿苷治疗不均性红细胞异形症和癫痫性脑病。尿苷具有多种生物学功能,例如可以治疗干眼症、调节神经系统和用于复制。高水平的尿苷与胰岛素抵抗有关。

基本信息

经验(实验)分子式C9H12N2O6
分子量244.20
Beilstein754902
EC 号200-407-5
MDL编号MFCD00006526
PubChem化学物质编号24900640
NACRESNA.51

产品性质

质量水平200
生物来源synthetic (organic)
测定≥99%
形式powder
mp163-167 ℃ (lit.)
溶解性H2O: 50 mg/mL, clear, colorless
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI keyDRTQHJPVMGBUCF-XVFCMESISA-N
Gene Informationmouse ... Uck1(22245)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
U3003Sigma-AldrichUridinepowder, BioReagent, suitable for cell culture788.74元/5 G;   4724.53元/50 G;   展开

产品说明

一般描述

尿苷是一种尿嘧啶核苷,对RNA序列具有特异性。尿苷存在于血液、精液和脑脊液中。尿苷是在生物体中从头和挽救途径合成核苷酸的底物。

应用

尿苷已用于:

  • 用作大鼠背根神经节(DRG)神经元培养物中施旺细胞增殖的抑制剂
  • 用作表皮细胞培养的培养基补充剂
  • 用作神经元培养的5-氟-2′-脱氧尿苷储备液组分

包装

5, 50 g in poly bottle

生化/生理作用

单磷酸尿苷对于蛋白质糖基化、多糖生物合成和脂质代谢至关重要。建议口服尿苷治疗异嗜红细胞增多症和癫痫性脑病。尿苷具有许多生物学功能,例如治疗干眼症、调节神经系统并促进生殖。高水平的尿苷可诱导胰岛素抵抗。

基本信息

经验(实验)分子式C9H12N2O6
分子量244.20
Beilstein754902
EC 号200-407-5
MDL编号MFCD00006526
PubChem化学物质编号24900638
NACRESNA.75

产品性质

质量水平200
生物来源synthetic (organic)
产品线BioReagent
测定≥99%
形式powder
technique(s)cell culture | mammalian: suitable
mp163-167 ℃ (lit.)
溶解性H2O: 50 mg/mL
web metadata keyword.defaultUMP precursor
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI keyDRTQHJPVMGBUCF-XVFCMESISA-N
Gene Informationmouse ... Uck1(22245)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
1707114USPUridineUnited States Pharmacopeia (USP) Reference Standard3572.92元/30 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C9H12N2O6
分子量244.20
Beilstein754902
MDL编号MFCD00006526
PubChem化学物质编号329751464
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp163-167 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI keyDRTQHJPVMGBUCF-XVFCMESISA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
U6381Sigma-AldrichUridineBioUltra, ≥99%1280.38元/5 G;   5108.21元/25 G;   展开

产品说明

一般描述

尿苷是一种嘧啶核苷,对 RNA 和膜的合成至关重要。它通过形成嘧啶核苷酸-脂质缀合物来帮助正常细胞功能和生长。

应用

尿苷已被用于研究原生动物寄生虫的核苷水解酶和哺乳动物尿苷磷酸化酶在酿酒酵母的URH1(尿苷水解酶)上的功能互补。
它已用于检查长期应用尿苷对小鼠肝脏代谢的影响。

包装

5, 25 g in poly bottle

基本信息

经验(实验)分子式C9H12N2O6
分子量244.20
Beilstein754902
EC 号200-407-5
MDL编号MFCD00006526
PubChem化学物质编号24900434
NACRESNA.26

产品性质

产品线BioUltra
质量水平200
测定≥99%
杂质≤0.005% Phosphorus (P)
≤0.1% Insoluble matter
灼烧残渣≤0.1%
mp163-167 ℃ (lit.)
溶解性H2O: 0.1 M, clear, colorless
痕量阳离子Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.005%
Mg: ≤0.003%
NH4+: ≤0.15%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI keyDRTQHJPVMGBUCF-XVFCMESISA-N
Gene Informationmouse ... Uck1(22245)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
V900421Sigma-AldrichUridineVetec, reagent grade, 99%298.44元/25 G;   1029.9元/100 G;   展开

产品说明

包装

25, 100 g in poly bottle

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

经验(实验)分子式C9H12N2O6
分子量244.20
Beilstein754902
MDL编号MFCD00006526
PubChem化学物质编号329829829

产品性质

等级reagent grade
产品线Vetec
测定99%
mp163-167 ℃ (lit.)
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI keyDRTQHJPVMGBUCF-XVFCMESISA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR2244SupelcoUridinePharmaceutical Secondary Standard; Certified Reference Material4856.38元/100 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3401 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C9H12N2O6
分子量244.20
Beilstein754902
MDL编号MFCD00006526

产品性质

等级certified reference material
pharmaceutical secondary standard
形式solid
CofAcurrent certificate can be downloaded
包装pkg of 100 mg
mp163-167 ℃ (lit.)
药典可追溯性traceable to USP 1707114
储存温度2-8℃
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI keyDRTQHJPVMGBUCF-XVFCMESISA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
078878FluorochemUridine98%220元/1g;   396元/25g;   836元/100g;   展开

基本信息

CAS Number58-96-8
MDL NumberMFCD00006526
Melting Point165-169℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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