| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| H923040 | MACKLIN | 羟基丙酮酸磷酸酯 锂盐 | 95% | 1564元/10mg; | 展开 |
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| 02711 | Sigma-Aldrich | Hydroxypyruvic acid phosphate lithium salt | ≥95% (HPLC) | 1170.62元/10MG; 3571.66元/50MG; | 展开 |
产品说明 生化/生理作用 L-丝氨酸可能有四种来源：饮食摄入、糖酵解中间体 3-磷酸甘油酸生物合成、甘氨酸以及蛋白质和磷脂降解。在生物合成途径中，在3-磷酸甘油酸脱氢酶(3-PGDH； EC 1.1.1.95)催化的反应下，糖酵解中间体3-磷酸甘油酸转化为磷酸羟基丙酮酸。磷酸羟基丙酮酸氨基转移酶(EC 2.6.1.52)将磷酸羟基丙酮酸代谢为磷酸丝氨酸，最后，磷酸丝氨酸磷酸酶(PSP； EC 3.1.3.3)将磷酸丝氨酸转化为L-丝氨酸。 在肝脏组织中，丝氨酸生物合成途径受饮食和激素变化的调节。在这三种合成酶中，以 3-PGDH 和 PSP 的属性记载最好。激素因素，如胰高血糖素和皮质类固醇也影响 3-PGDH 和 PSP 的活动的相互作用依赖于饮食。L-丝氨酸在细胞增殖中发挥核心角色。L-丝氨酸是嘌呤核苷酸和脱氧胸苷一磷酸从头合成的一碳基团的主要来源。长期以来，人们认识到，在细胞培养物中，L-丝氨酸是一种条件性必需氨基酸，因为它不能合成足够数量以满足细胞对其利用的需求。近年来，L-丝氨酸及其代谢产物被认为不仅是细胞增殖所必需的，而且是中枢神经系统特定功能所必需的。精神疾病患者丝氨酸和甘氨酸水平改变以及 L-丝氨酸合成缺陷患者的严重神经系统异常的发现强调了 L-丝氨酸在大脑发育和功能中的重要性；例如阿尔茨海默病s 病 、精神分裂症 、心力衰竭 和青少年肌阵挛性癫痫 。 基本信息 | 经验(实验)分子式 | C3H5O7P · xLi+ | | 分子量 | 184.04 (free acid basis) | | MDL编号 | MFCD20652972 | | PubChem化学物质编号 | 329747499 | | NACRES | NA.25 |
产品性质 | 质量水平 | 100 | | 测定 | ≥95% (HPLC)
5.0-14.0% (lithium, ICP) | | 杂质 | ≤8.0% water | | 储存温度 | −20℃ | | SMILES string | O=C(O)C(COP(O)(O)=O)=O | | InChI | 1S/C3H5O7P/c4-2(3(5)6)1-10-11(7,8)9/h1H2,(H,5,6)(H2,7,8,9) | | InChI key | LFLUCDOSQPJJBE-UHFFFAOYSA-N |
安全信息 | 象形图 |  | | 警示用语： | Warning | | 危险声明 | H302 + H312 | | 预防措施声明 | P264 - P270 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364 | | 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 529553 | Fluorochem | 3-HYDROXY-2,2-DIMETHOXY-PROPANOICACID3-PHOSPHATETRI(CYCLOHEXYLAMMONIUM)SALT | 95% | 6578元/250mg; 16412元/1g; 49236元/5g; | 展开 |
基本信息 | CAS Number | 3913-50-6 | | MDL Number | MFCD00058333 | | Density | 1.93 |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H360: May damage fertility or the unborn child ..
| | 防范说明 | P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe
P261: Avoid breathing .
P264: Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear .
P281: Use personal protective equipment as required.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P363: Wash contaminated clothing before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations..
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