CAS 334827-98-4; gisadenafil besylate salt

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CAS:

334827-98-4

分子式:

C₂₉H₃₉N₇O₈S₂

分子量:

677.79

英文名称:

gisadenafil besylate salt

uk 369003-26

uk 369003

5-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7h-pyrazolo[4,3-d]pyrimidin-7-one benzenesulfonate besylate salt

用途:

Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor (IC50, 3.6 nM). Gisadenafil besylate inhibits cyclic guanosine monophosphate (cGMP) degradation.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

G912361

MACKLIN

Gisadenafil besylate (UK 369003-26)

≥98%

1264元/1mg;

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储存：-20°C，密闭，干燥

PZ0172

Sigma-Aldrich

Gisadenafil besylate salt

≥98% (HPLC)

1364.72元/5 MG; 5158.2元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Gisadenafil (UK 369003) is a PDE5 inhibitor. It is 80 fold selective over PDE6, and greater than 3000 fold selective over PDEs 1-4 and 7.

特点和优势

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

其他说明

This compound was developed by Pfizer for Cyclic Nucleotides research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₃H₃₃N₇O₅S · C₆H₆O₃S
分子量	677.79
MDL编号	MFCD18384964
PubChem化学物质编号	329823746
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
manufacturer/tradename	Pfizer^®
颜色	white to off-white
溶解性	DMSO: >35 mg/mL
创始人	Pfizer
储存温度	2-8℃
SMILES string	OS(=O)(=O)c1ccccc1.CCOc2ncc(cc2C3=NC(=O)c4nn(CCOC)c(CC)c4N3)S(=O)(=O)N5CCN(CC)CC5
InChI	1S/C23H33N7O5S.C6H6O3S/c1-5-18-19-20(27-30(18)12-13-34-4)22(31)26-21(25-19)17-14-16(15-24-23(17)35-7-3)36(32,33)29-10-8-28(6-2)9-11-29;7-10(8,9)6-4-2-1-3-5-6/h14-15H,5-13H2,1-4H3,(H,25,26,31);1-5H,(H,7,8,9)
InChI key	STFRDYSZKVPPQF-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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