| CAS: | 329221-38-7 | ||
| 分子式: | C13H16N2O2S | ||
| 分子量: | 264.34 | ||
| 英文名称: |
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| 用途: | AX20017是蛋白激酶G (PknG) 的小分子抑制剂，IC50 值为 0.39 μM。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||
| A879559 | MACKLIN | AX20017 | ≥99% | 343元/5mg; 530元/10mg; 1927元/50mg; | 展开 | ||||||||||||||||||||||||||||||||
储存：2-8℃ | |||||||||||||||||||||||||||||||||||||
| 370653 | Sigma-Aldrich | PknG Inhibitor-CAS 329221-38-7-Calbiochem | The PknG Inhibitor, also referenced under CAS 329221-38-7, controls the biological activity of PknG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica | 2165.23元/10 MG; | 展开 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable tetrahydrobenzothiophene compound that acts as a highly specific and ATP-binding site-targeting inhibitor against mycobacterial protein kinase G (PknG; IC50 = 390 nM), while exhibiting much reduced or no activity against 8 other mycobacterial and 25 other human kinases, including PKCα, the mammalian kinase most closely related to PknG. AX20017 is shown to completely inactivate PknG-mediated blockage of lysosomal transfer and degradation of M. bovis BCG in macrophages at concentrations (10µM or higher) that does not otherwise affect the growth of BCG outside its infected host. 包装 10 mg in Plastic ampoule 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 其他说明 Scherr, N., et al. 2007. Proc. Natl. Acad. Sci. USA104, 16388. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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