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CAS: 152787-58-1
英文名称: 
trka (440-end), active, gst tagged human
trk1
dkfzp781l14186
ntrk1
p140-trka
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货号品牌产品名称规格包装、参考价格详情
T4202Sigma-AldrichTRKA (440-end), active, GST tagged humanPRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution6484.55元/10 μG;   展开

产品说明

应用

TRKA (440-end), active, GST tagged human was used to study functional NGF signal transduction.

生化/生理作用

TRKA (440-end), active, GST tagged human is a 140 kD membrane-spanning protein tyrosine kinase that belongs to proto-oncogene family. TRKA facilitates the regulation of cell differentiation and survival via activating SHC1 and FRS2 which in turn activates a GRB2-Ras-MAPK cascade. It also plays a pivotal role in controlling NF-κ-B activation as well as transcription of genes involved in cell survival via PLCG1.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

质量水平200
生物来源human
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity19-25 nmol/min·mg
分子量 ~66 kDa
technique(s)activity assay: suitable
UniProt登记号P04629
运输dry ice
储存温度−70℃
Gene Informationhuman ... NTRK1(4914)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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