CAS: | 1523001-32-2 | ||
英文名称: |
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货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||||
H2167 | Sigma-Aldrich | Histone H2B human | 1141.56元/100 μG; | 展开 | |||||||||||||||||||||||||||||||||||||||||||
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H2542 | Sigma-Aldrich | Histone H3.3 human | 1120.02元/100 μG; | 展开 | |||||||||||||||||||||||||||||||||||||||||||
产品说明 其他说明 Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA, and 1 mM DTT. 基本信息
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H2667 | Sigma-Aldrich | Histone H4 human | 1093.41元/100 μG; | 展开 | |||||||||||||||||||||||||||||||||||||||||||
产品说明 其他说明 Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA 基本信息
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H1917 | Sigma-Aldrich | Histone H1 human | 1082.01元/100 μG; | 展开 | |||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Histone H1 is part of high-order chromatin structure and is a linker protein associated with nucleosome core particle. Histone H1 is mapped to human chromosome 6. Histone H1 exists in different isoforms. Histone H1 comprises of N-terminal hydrophobic rich region, central globular domain and a C-terminal with intrinsically disordered regions. 生化/生理作用 The C-terminal regions of histone H1 is essential for binding to chromatin. The placement of H1 is necessary for nucleosome positioning. Histone H1 maintains chromosome architecture and stabilises compaction of nucleosomes during interphase. H1-null mutants display increased rate of chromatin aberration and growth defects. Histone H1 modulates embryogenesis and DNA repair. The H1 histone undergoes posttranslational modification including phosphorylation, methylation and acetylation, each of which carry out different physiological functions. Histone H1 and its variants contribute to the pathogenesis in cancer, Alzheimer′s disease, male infertility and immunity related disorders. 外形 Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA, and 1 mM DTT. 基本信息
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H2042 | Sigma-Aldrich | Histone H2A human | 1141.56元/100 μG; | 展开 | |||||||||||||||||||||||||||||||||||||||||||
产品说明 外形 Supplied in 20 mM Na3PO4, pH 7.0, 0.3 M NaCl and 1 mM EDTA 基本信息
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H2292 | Sigma-Aldrich | Histone H3.1 human | 1141.56元/100 μG; | 展开 | |||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Histone H3.1 is a histone H3 variant. It differs from H3.2 with residue 96 being a cysteine instead of serine. H3.1 is a replication-dependent histone and is a component of nucleosomes during the S-phase. 应用 Histone H3.1 human has been used in in vitro Schizosaccharomyces pombe Set7 histone methyltransferase assay for matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) studies. 生化/生理作用 Histone H3.1 human (H3.1) undergoes a majority of post-translational modification especially acetylation and demethylation in lysine 14 and 9 respectively. During differentiation, the levels of H3.1 transcripts decrease as cell division slows down. The incorporation of H3.1 into chromatin is mediated by a chaperone, chromatin assembly factor (CAF-1). A transversion mutation in the H3.1 may be implicated in glioma. 外形 Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA, and 1 mM DTT. 基本信息
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