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CAS: 132705-51-2
分子式: C12H24BrF6N3P2
分子量: 466.18
熔点: 100℃
中文名称: 
三吡咯烷基溴化鏻六氟磷酸盐
溴-三吡咯烷基磷代六氟磷酸酯
英文名称: 
PYBROP
Bromotripyrrolidinophosphonium hexafluorophosphate
Bromotri(pyrrolidino)phosphonium hexafluorophosphate
bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
推荐供应商
货号品牌产品名称规格包装、参考价格详情
B802929MACKLIN三吡咯烷基溴化鏻六氟磷酸盐98%25元/1g;   51元/5g;   232元/25g;   899元/100g;   展开
储存:-20°C
状态:无色或白色到灰白色粉末或晶体
B2680TCIBromotripyrrolidinophosphonium Hexafluorophosphate>98.0%(HPLC)(N)815元/5G;   2545元/25G;   展开

基本信息

纯度/分析方法>98.0%(HPLC)(N)
分子式/分子量C12H24BrF6N3P2 = 466.19
外观与形状(20℃)固体
储存温度<0℃
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解),加热
Reaxys-RN6842340
PubChem物质ID160871368
MDL编号MFCD00077412

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(with Total Nitrogen)min. 98.0 %

物性(参考值)

熔点139 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
241290J&KBromo-tris-pyrrolidino-phosphonium hexafluorophosphate97%94元/1G;   376元/5G;   1365元/25G;   展开

基本信息

分子式C12H24BrN3P·PF6
分子量466.18
熔点>100
MDL编码MFCD00077412
Beilstein6842340
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Danger
危险说明H314
防范说明P280
P305+P351+P338
P310
WGK3
TSCA
L19384Alfa AesarBromotri(1-pyrrolidinyl)phosphonium hexafluorophosphate97%544元/1g;   1983元/5g;   展开

基本信息

MDL
MFCD00077412

EINECS
000-000-0

分子式
C12H24BrF6N3P2

分子量
466.19

灵敏度
Store at -20°C. Moisture Sensitive.

Beilstein
7845702

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA

18565Sigma-AldrichBromotripyrrolidinophosphonium Hexafluorophosphate≥95.0% (HPLC)255.05元/1 G;   1066.87元/5 G;   3265.03元/25 G;   展开

产品说明

应用

用于催化:
伯酰胺的合成
直接脱水鏻交叉偶联
直接芳香化
通过鏻盐偶联剂形成吡咯烷
它可用作偶联剂:

  • 酚与芳基硼酸的Suzuki-Miyaura交叉偶联合成联芳和杂联芳。
  • 通过使用各种亲核试剂功能化修饰嘧啶(由3,4-二氢嘧啶-2(1H)-酮(DHPM)通过Kappe脱氢反应合成)。
  • 通过与各种伯胺和N,N-二异丙基乙胺偶联来合成甲脒。

它也可以用作激活剂:
  • 激活可互变异构杂环中的C-OH键以形成有助于杂环和各种炔烃的Sonogashira 偶联反应的膦盐。
  • 酚中C-O键的一锅激活(one-pot activation)并进一步与膦氧化物或亚磷酸盐进行偶联反应生成C-P键。

包装

5, 25 g in poly bottle
1 g in poly tube

其他说明

适用于α ,α -二烷基氨基酸的活性肽偶联剂;缩酚酸肽的合成

法律信息

PyBroP is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C12H24BrF6N3P2
分子量466.18
Beilstein6842340
MDL编号MFCD00077412
PubChem化学物质编号57647747
NACRESNA.22

产品性质

质量水平100
测定≥95.0% (HPLC)
reaction suitabilityreaction type: Coupling Reactions
application(s)peptide synthesis
储存温度−20℃
SMILES stringF[P-](F)(F)(F)(F)F.Br[P+](N1CCCC1)(N2CCCC2)N3CCCC3
InChI1S/C12H24BrN3P.F6P/c13-17(14-7-1-2-8-14,15-9-3-4-10-15)16-11-5-6-12-16;1-7(2,3,4,5)6/h1-12H2;/q+1;-1
InChI keyCYKRMWNZYOIJCH-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H314
预防措施声明P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310
危险分类Eye Dam. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
384771AmethystBromo-tris-pyrrolidino-phosphonium hexafluorophosphate97%, 用于合成55元/1G;   114元/5G;   383元/25G;   1239元/100G;   展开

基本信息

分子式C12H24BrN3P·PF6
分子量466.18
熔点>100
MDL编码MFCD00077412
Beilstein6842340
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Danger
危险说明H314
防范说明P280
P305+P351+P338
P310
WGK3
TSCA
024897FluorochemBromo-tris-pyrrolidino-phosphonium hexafluorophosphate99%396元/5g;   902元/25g;   2970元/100g;   展开

基本信息

CAS Number132705-51-2
MDL NumberMFCD00077412

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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