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CAS: 132201-33-3
分子式: C16H15NO4
分子量: 285.29
熔点: 169-172 °C
中文名称: 
直链型紫杉醇侧链
英文名称: 
n-benzoyl-(2R,3S)-3-phenylisoserine
用途: N-Benzoyl-(2R,3S)-3-phenylisoserine, also known as taxol side chain, is important for strong antitumor activity of taxol.
推荐供应商
货号品牌产品名称规格包装、参考价格详情
N793645MACKLIN紫杉醇侧链10mM in DMSO185元/1ml;   展开
储存:-20°C
状态:液体
N873827MACKLIN紫杉醇侧链97%112元/250mg;   293元/1g;   851元/5g;   2813元/25g;   8989元/100g;   展开
储存:-20℃
状态:白色到灰白色粉末,晶体和/或块状
444375Sigma-AldrichN-Benzoyl-(2R,3S)-3-phenylisoserine98%827.97元/500 MG;   展开

产品说明

应用

已经证明,该手性侧链的存在对于紫杉醇的生物活性至关重要, 紫杉醇是目前正在研究的最有潜力的抗癌药之一。 紫杉醇复杂的合成过程已经引起人们对在天然衍生紫杉烷类(例如,巴卡亭 III)上附接 C-13 侧链的关注。

包装

500 mg in glass insert

基本信息

线性分子式C6H5CONHCH(C6H5)CH(OH)CO2H
分子量285.29
MDL编号MFCD00274633
eCl@ss32160406
PubChem化学物质编号24868119
NACRESNA.22

产品性质

质量水平100
测定98%
旋光性[α]20/D −40°, c = 1.0 in ethanol
reaction suitabilityreaction type: solution phase peptide synthesis
mp169-172 ℃ (lit.)
application(s)peptide synthesis
SMILES stringO[C@H]([C@@H](NC(=O)c1ccccc1)c2ccccc2)C(O)=O
InChI1S/C16H15NO4/c18-14(16(20)21)13(11-7-3-1-4-8-11)17-15(19)12-9-5-2-6-10-12/h1-10,13-14,18H,(H,17,19)(H,20,21)/t13-,14+/m0/s1
InChI keyHYJVYOWKYPNSTK-UONOGXRCSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
212819Fluorochem(2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoic acid95%968元/1g;   2772元/5g;   4686元/10g;   9174元/25g;   展开

基本信息

CAS Number132201-33-3
MDL NumberMFCD00274633
Melting Point169-172℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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