CAS 100678-32-8; butanedioic acid, compd. with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidaz

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CAS:

100678-32-8

分子式:

C₁₈H₁₈N₂ ·C₄H₆O₄

分子量:

380.44

英文名称:

butanedioic acid, compd. with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidaz

ole (1:1)

(+-)-2-(2,2-diphenylcyclopropyl)-2-imidazoline succinate (1:1)

2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazol (+-)-1h-imidazol butanedioate (

1:1)

4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazol succinate

4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazole succinate

cibenzoline succinate (1:1)

cifenline succinate

cipralan

ritmalan

ro 22-7796/001

butanedioic acid, compd. with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazole (1:1)

cibenzoline succinate

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用途:

Cibenzoline also called (±)-2-(2,2-diphenylcyclopropyl)-2-imidazoline succinate, is generally used in stereo combination of R(+) and S(−) forms. It also exhibits anticholinergic activity.. Cibenzoline is known to improve left ventricular diastolic dysfunction by reducing left ventricular pressure gradient.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

C920569

MACKLIN

琥珀酸西苯唑啉

≥98% (HPLC)

1785元/10mg;

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储存：2-8°C
状态：固体

C1618

Sigma-Aldrich

Cibenzoline succinate

≥98% (HPLC), solid

2231.72元/10 MG; 7124.33元/50 MG;

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产品说明

一般描述

Cibenzoline also called (±)-2-(2,2-diphenylcyclopropyl)-2-imidazoline succinate, is generally used in stereo combination of R(+) and S(−) forms. It also exhibits anticholinergic activity.. Cibenzoline is known to improve left ventricular diastolic dysfunction by reducing left ventricular pressure gradient.

包装

10, 50 mg in glass bottle

生化/生理作用

Cibenzoline is a class IA antiarrhythmic drug. Cibenzoline (μM concentrations) blocks ATP-sensitive K channels in heart and pancreatic cells. Cibenzoline interacts with the channel pore-forming subunit of the K(ATP) channel (Kir6.2) from the cytoplasmic side. Cibenzoline also inhibits the delayed rectifier K current [I(Kr)] in sino-atrial node cells.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₈H₁₈N₂·C₄H₆O₄
分子量	380.44
MDL编号	MFCD00941423
PubChem化学物质编号	24892426
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
储存条件	desiccated
颜色	white to brown
溶解性	H₂O: ≥5 mg/mL
储存温度	2-8℃
SMILES string	OC(=O)CCC(O)=O.C1CN=C(N1)C2CC2(c3ccccc3)c4ccccc4
InChI	1S/C18H18N2.C4H6O4/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17;5-3(6)1-2-4(7)8/h1-10,16H,11-13H2,(H,19,20);1-2H2,(H,5,6)(H,7,8)
InChI key	XFUIOIWYMHEPIE-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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