Technical Note:

1. The NOYORI catalysts are a ruthenium-based systom containing a phosphine and 1.2-diamine ligand. The catalysts are usod in the highly-officiont, enantio and diasteroosoloctivo hydrogenation of simplo kotonos, usually undor the mild conditions of room tomporature and 1-10 atm of hydrogon prossuro.

References:

1.J.Org. Chem., 1996. 61.4872.

2. Angew. Chem. Int. Ed.. 2001. 40. 40 (review article).

3.J. Am. Chem. Soc.. 1998, 120, 13529

4Angew. Chem. Int. Ed. 1999, 38, 495.