Technical Notes:

1.Biaryl bisphosphine ligand.The H8-BINAP ligand,as the ruthenium complex, catalyzes hydrogenation of unsaturated carboxylic acids to a higher ee than does BINAP.(Ref.1.2)

2.The ruthenium catalyzed hydrogenation of aryl propenoic acid to produce the drug lbuprofen.

3.Rhodium catalyzed asymmetric regioselective 1.4-addition of arylboronic acids to 3-substituted maleimides

4.Ligand for palladium-catalyzed enantioselective hydrogenation of substituted indoles.

5.Rhodium-catalyzed enantioselective cyclization of Y-alkynylaldehydes with acyl phosphonates.

6.Enantioselective synthesis of axially chiral 1-arylisoquinolines by Rh-catalyzed 2+2+2 cycloaddition.

7.Enantioselective synthesis of 2.3-disubstituted indolines through Bronsted acid/Pd-complex-promoted tandem reactions

8.Dehydration triggered asymmetric hydrogenation of 3-(a-hydroxyalkyl)indoles

9.lridium-catalyzed2+2+2 cycloaddition of a,w-diynes with arylisocyanates

10.Asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)-indoles

11.Asymmetric Rh(1-catalyzed intramolecular 3+2 cycloaddition of 1-yne-vinylcyclopropanes for bicyclo3.3.0 compounds with

a chiral quaternary carbon stereocenter.

12. Enantioselective intermolecular2+2+2 cycloadditions of ene-allenes with allenoates

13.Rh-catalyzed one-pot intermolecular 2+2+2 trimerization/asymmetric intramolecular 4+2 cycloaddition of two aryl ethynyl

ethers and 5-alkynals.

14.Rh-catalyzed regio-, diastereo-, and enantioselective 2+2+2 cycloaddition of 1.6-enynes with acrylamides.