Technical Note:

1.Air and moisture-stable phosphonium salt used in palladium-catalyzed coupling reactions. The phosphoniumsaltis s deprotonated in situ to yield the free phosphine ligand. Use of the phosphonium salt furnished nearly identical product as reactions carried out using the phosphine.

2. Ligand for the Pd-catalyzed heteroaromatic direct arylation.

References: 1.J. Am. Chem. Soc., 2003, 125, 5616. 2.J. Am. hem. Soc., 2003, 125, 371 8. 3.Angew. Chem. Int. Ed., 2002, 41, 3910. 4.J. Am. Chem. Soc., 2002, 124, 13662. 5.Angew. Chem. Int. Ed., 2011, 50, 8660. 6.J. Org. Chem., 2010, 75, 1047.