| 包装 | 价格 | |
| 25MG | 184元 | 留言咨询 |
| 100MG | 443元 | 留言咨询 |
产品描述
(R)-baclofen是一种γ-氨基丁酸衍生物，主要用于治疗痉挛。
靶点（IC50 & Targe）
GABAR
体外研究
Baclofen is a skeletal muscle relaxant used in the treatment of spasticity of spinal and cerebral origin. Although it is marketed as a racemic mixture, only the baclofen R-enantiomer is stereospecifically active at so called GAGAB-receptors. Researchers believe that the enantiomers of baclofen have different properties. It is claimed that the R-(−)-enantiomer is about 100 times more active than the S-(+)-enantiomer.
参考文献
[1] Falch E, et al. J Neurochem, 1986, 47(3), 898-903.
[2] Penn RD, et al. Lancet, 1984, 1(8385), 1078.
