产品介绍 基因名： ARID4B 产品别名： BCAA； BRCAA1； RBBP1L1； RBP1L1； SAP180； ARID4B； AT-rich interaction domain 4B； AT-rich interaction domain 4B； AT-rich interactive domain-containing protein 4B； 180 kDa Sin3-associated polypeptide； ARID domain-containing protein 4B； AT rich interactive domain 4B (RBP1-like)； Rb-binding protein homolog； SIN3A-associated protein 180； breast cancer-associated antigen 1； breast cancer-associated antigen BRCAA1； breast carcinoma-associated antigen； histone deacetylase complex subunit SAP180； retinoblastoma-binding protein 1-like 1； sin3-associated polypeptide p180； 乳腺癌相关抗原BRCAA1； 背景信息： This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]. 标签：His-tag |
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