产品介绍 基因名： Asap1 产品别名： AV239055； DEF-1； Ddef1； PAP； mKIAA1249； s19； Asap1； ArfGAP with SH3 domain, ankyrin repeat and PH domain1； ArfGAP with SH3 domain, ankyrin repeat and PH domain1； arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1； 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein； 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein； ADP-ribosylation factor-directed GTPase-activating protein 1； ARF GTPase-activating protein 1； PIP2-dependent ARF1 GAP； development and differentiation-enhancing factor 1； 发育分化增强因子1； 磷酸化发育分化增强因子1； 背景信息： ADP-ribosylation factor (Arf) family of small GTP-binding proteins plays a central role in membrane trafficking and cytoskeletal remodeling. ASAP1 (Arf-GAP containing SH3, ankyrin repeats and PH domain) is a phospholipid-dependent Arf GTPase-activating protein that binds to the protein-tyrosine kinases Src and focal adhesion kinase. ASAP1 may act as an oncogene in cancer, and it may be a useful diagnostic marker and therapeutic target. 标签：His-tag |
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