试剂仪器设备原料
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蛋白质/抗原/多肽 >> 重组蛋白
重组蛋白转运抑制剂GBF1
重组蛋白转运抑制剂GBF1图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant GBF1
Recombinant golgi brefeldin A resistant guanine nucleotide exchange factor 1 protein
产品介绍
基因名:

GBF1


产品别名:

ARF1GEF; CMT2GG; GBF1; golgi brefeldin A resistant guanine nucleotide exchange factor 1; golgi brefeldin A resistant guanine nucleotide exchange factor 1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; BFA-resistant GEF 1; 蛋白转运抑制剂GBF1;


背景信息:
Protein trafficking to the membrane requires formation of coated carrier vesicles, such as COPI-coated vesicles from the cis-golgi, a process triggered by membrane binding of the GTP-bound form of ADP-ribosylation factors. Normally, brefeldin A (BFA) blocks this action by inhibiting guanine nucleotide exchange factors (GEFs) for ADP-ribosylation factor. However, GBF1, a member of the sec7-domain family of GEFs, allows cells to maintain normal golgi morphology and grow in the presence of BFA. The gene encoding the human GBF1 protein maps to chromosome 10q24, with the sec7-domain centrally positioned, and a proline-rich C-terminus. Based on mutatagenesis analysis, this proline rich region appears to interact with p115 in a functionally significant manner.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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