产品介绍 靶标： XAGE1B 产品别名： CT12.1； CT12.1C； CT12.1D； CT12.1E； CT12.1b； CTP9； GAGED2； XAGE-1； XAGE1； XAGE1C； XAGE1D； XAGE1E； XAGE1B； X antigen family member 1B； X antigen family member 1B； X antigen family member 1； G antigen family D member 2； X antigen family member 1E； X antigen family, member 1C； X antigen family, member 1D； cancer/testis antigen 12.1； cancer/testis antigen family 12, member 1b； cancer/testis antigen family 12, member 1c； cancer/testis antigen family 12, member 1d； cancer/testis antigen family 12, member 1e； cancer/testis associated protein； protein XAGE-1； 背景信息： XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites. 宿主：Rbt |
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