产品介绍 靶标： ZNF395 产品别名： HDBP-2； HDBP2； HDRF-2； PBF； PRF-1； PRF1； Si-1-8-14； ZNF395； zinc finger protein 395； zinc finger protein 395； zinc finger protein 395； HD gene regulatory region-binding protein 2； HD-regulating factor 2； Huntington's disease gene regulatory region-binding protein 2； huntington disease gene regulatory region-binding protein 2； papillomavirus regulatory factor 1； papillomavirus regulatory factor PRF-1； papillomavirus-binding factor； 锌指蛋白395； 背景信息： Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3??-CCGG-5?? sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm. 宿主：Rbt |
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